Rotura pancreática completa secundaria a traumatismo abdominal cerrado / Complete rupture of the pancreas due to blunt abdominal trauma

No disponible

Neumonía por aspiración diagnosticada mediante gammagrafía SPECT/TAC de tránsito esofágico / Aspiration pneumonia diagnosed by esophageal transit SPECT/CT scintigraphy

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Evaluación longitudinal con FP-CIT en pacientes con parkinsonismo / Longitudinal evaluation using FP-CIT in patients with parkinsonism

Objetivo: Analizar un grupo de pacientes con síndrome parkinsoniano mediante estudios seriados con FP-CIT, valorando fundamentalmente los resultados falsamente negativos iniciales. Métodos: Estudio retrospectivo en el que se incluye a 92 pacientes (55 varones y 37 mujeres), a los que se les realizó un doble estudio con FP-CIT pues existían discrepancias entre este y la evolución clínica del paciente. El tiempo medio ± desviación estándar transcurrido entre ambos estudios fue de 26 ± 6 meses. Se realizó una valoración semicuantitativa analizando mediante la historia clínica y la bibliografía disponible los casos discrepantes con estudio inicial normal y posterior patológico. Resultados: Del total de 184 estudios realizados a 92 pacientes, 11/92 mostraron resultados discrepantes entre estudio inicial y tardío. De estos, en 7/11 el estudio inicial fue normal y el posterior patológico. Los rasgos clínicos predominantes que pudieran explicar este comportamiento mostraron que en 4/7 sujetos destacó la presentación de un cuadro parkinsoniano con predominio de la clínica tremórica; 1/7 presentó un síndrome parkinsoniano en estadio inicial en tratamiento con fármaco antidopaminérgico, 1/7 fue catalogado de probable atrofia multisistema tipo C y 1/7 presentaba un cuadro de parkinsonismo atípico, sin que encontráramos justificación para dicho comportamiento. Conclusiones: La realización de estudios seriados con FP-CIT carece de fundamento en gran proporción de casos, aunque existen ciertas situaciones clínicas que pueden justificarlo

Objective: To assess a group of patients with parkinsonism using serial studies with FP-CIT, basically the initial false negative results. Methods: Restrospective study of 92 patients (55 men and 37 women) who had undergone 2 different FP-CIT studies because of discrepancies between study results and clinical progression. The mean elapsed time between the studies was 26 months (SD: 6). We performed a semi-quantitative study using the patient's clinical history and the available literature to analyse discrepant cases with a normal initial study and subsequent pathological findings. Results: A total of 184 studies were completed for 92 patients; 11 of those 92 showed discrepancies between initial and subsequent studies. Among the 11 discrepant cases, 7 showed a normal initial study and pathological findings at a later date. Analysis of the predominant clinical features that might explain this behaviour revealed that 4 of these 7 subjects presented tremor-dominant parkinsonism. Regarding the rest, 1 presented early stage parkinsonism and was treated with antidopaminergic agents; 1 was classified as probable multisystem atrophy type C, and the third showed clinical signs of atypical parkinsonism without any causes of those signs being identified. Conclusions: Serial FP-CIT studies are unnecessary in the large majority of cases, but they may be justifiable in certain clinical situations

Longitudinal evaluation using FP-CIT in patients with parkinsonism.

OBJECTIVE: To assess a group of patients with parkinsonism using serial studies with FP-CIT, basically the initial false negative results. METHODS: Restrospective study of 92 patients (55 men and 37 women) who had undergone 2 different FP-CIT studies because of discrepancies between study results and clinical progression. The mean elapsed time between the studies was 26 months (SD: 6). We performed a semi-quantitative study using the patient's clinical history and the available literature to analyse discrepant cases with a normal initial study and subsequent pathological findings. RESULTS: A total of 184 studies were completed for 92 patients; 11 of those 92 showed discrepancies between initial and subsequent studies. Among the 11 discrepant cases, 7 showed a normal initial study and pathological findings at a later date. Analysis of the predominant clinical features that might explain this behaviour revealed that 4 of these 7 subjects presented tremor-dominant parkinsonism. Regarding the rest, 1 presented early stage parkinsonism and was treated with antidopaminergic agents; 1 was classified as probable multisystem atrophy type C, and the third showed clinical signs of atypical parkinsonism without any causes of those signs being identified. CONCLUSIONS: Serial FP-CIT studies are unnecessary in the large majority of cases, but they may be justifiable in certain clinical situations.